One of OSDP's improvements over Wiegand is the ability to Daisy-Chain multiple readers together and then connect those readers to one reader/OSDP input port on the controller. See our OSDP Access Control Guide for more.
You can often connect 2 - 8 readers together using OSDP versus only 1 for each port using Wiegand. Here's an image to show the concept:
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